Betty K Samulitis Selected Research

4- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- one

4/2012	Anti-tumor activity and mechanism of action for a cyanoaziridine-derivative, AMP423.
3/2012	Imexon induces an oxidative endoplasmic reticulum stress response in pancreatic cancer cells.
9/2011	Interaction of dacarbazine and imexon, in vitro and in vivo, in human A375 melanoma cells.
1/2011	Imexon enhances gemcitabine cytotoxicity by inhibition of ribonucleotide reductase.
2/2009	Inhibition of protein synthesis by imexon reduces HIF-1alpha expression in normoxic and hypoxic pancreatic cancer cells.
11/2006	Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice.
1/2006	Correlates of imexon sensitivity in human multiple myeloma cell lines.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Betty K Samulitis Research Topics

Disease

7	Neoplasms (Cancer) 12/2013 - 11/2006
5	Pancreatic Neoplasms (Pancreatic Cancer) 01/2015 - 02/2009
3	Necrosis 06/2013 - 01/2006
2	Multiple Myeloma 12/2013 - 01/2006
2	Lymphoma (Lymphomas) 05/2012 - 07/2006
1	Hypersensitivity (Allergy) 01/2015
1	Prostatic Neoplasms (Prostate Cancer) 12/2013
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2013
1	Colonic Neoplasms (Colon Cancer) 06/2013
1	Inflammation (Inflammations) 05/2012
1	B-Cell Lymphoma (Lymphoma, B Cell) 04/2012
1	Melanoma (Melanoma, Malignant) 09/2011
1	Hypoxia (Hypoxemia) 02/2009

Drug/Important Bio-Agent (IBA)

7	4- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- oneIBA 04/2012 - 01/2006
6	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2012 - 11/2006
3	Proteins (Proteins, Gene)FDA Link 04/2012 - 02/2009
2	Gemcitabine FDA Link 01/2015 - 01/2011
2	Pharmaceutical PreparationsIBA 05/2012 - 01/2006
2	Vincristine (Oncovin)FDA LinkGeneric 05/2012 - 07/2006
2	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2012 - 07/2006
2	GlucocorticoidsIBA 05/2012 - 07/2006
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/2012 - 07/2006
2	Sulfhydryl Compounds (Thiols)IBA 02/2009 - 11/2006
1	Histone Deacetylase InhibitorsIBA 01/2015
1	HeterochromatinIBA 01/2015
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2015
1	Antineoplastic Agents (Antineoplastics)IBA 12/2013
1	TubulinIBA 12/2013
1	5- (4- methoxyphenyl)- 2- (3- (3- methoxyphenyl)pyridin- 4- yl)oxazoleIBA 12/2013
1	OxazolesIBA 12/2013
1	CaspasesIBA 06/2013
1	3-((4-benzylpiperazino)methyl)-1H-indoleIBA 06/2013
1	EnzymesIBA 05/2012
1	AntioxidantsIBA 05/2012
1	AMP423IBA 04/2012
1	Peptide Initiation Factors (Initiation Factor)IBA 03/2012
1	Glutathione (Reduced Glutathione)IBA 03/2012
1	Dacarbazine (DIC)FDA LinkGeneric 09/2011
1	Drug CombinationsIBA 01/2011
1	Oxygen (Dioxygen)IBA 02/2009
1	CatalaseIBA 07/2006
1	Glutathione PeroxidaseIBA 07/2006
1	Oxidoreductases (Dehydrogenase)IBA 07/2006
1	Glucose (Dextrose)FDA LinkGeneric 07/2006
1	Adenosine Triphosphate (ATP)IBA 07/2006
1	FITC-annexin A5IBA 01/2006
1	Biological ProductsIBA 01/2006

Therapy/Procedure

1	Therapeutics 01/2015
1	Drug Therapy (Chemotherapy) 05/2012